Intro & build description
The poisonous concoction is a relatively new skill that has been really shining as a great mapping and league starter build. If you want a smooth league start with the ability to breeze through the Atlas, this Pathfinder build will be a perfect choice for 3.19 Lake of Kalandra.
Build Pros
- Great as a league starter - doesn't require any specific items to work
- Can clear all map mods
- Fast map clear
- The build is not specifically designed as a boss killer, but it can do Shaper, Elder, and guardians with basic life + resistance gear
- Reflect is not an issue
- Scales really well with currency investments
Build Cons
- Getting good cluster jewels will be quite hard very early in the league
Passive tree(s) and Path of Building
[3.19] Skill Tree PoB CommunityBandits
Bandits Quest Choice |
Kill all bandits |
Ascendancy skill points
Labyrinths | Skill point choice |
---|---|
Labyrinth 1 | Master Toxicist |
Labyrinth 2 | Nature's Reprisal |
Labyrinth 3 | Nature's Adrenaline |
Endgame Labyrinth | Nature's Boon |

Skill gem setup
Helm
Plague Bearer
Increased Area of Effect Support
Void Manipulation Support
Body Armor
Poisonous Concoction
Awakened Greater Multiple Projectiles Support
Awakened Vicious Projectiles
Awakened Void Manipulation
Awakened Unbound Ailments
Lifetap Support
Gloves
Increased Duration Support
Wither
Spell Totem Support
Multiple Totems Support
Boots
Vaal Molten Shell
Blood Rage
Malevolence
Increased Duration Support
2h Weapon
None
1h Weapon
None
Offhand weapon / shield
Flame Dash
Grace
Defiance Banner
Build uniques / Example rare gear
Tip: Click on the item to view it on PoE Wiki or to view similar rare items in poe.tradeHelmet
Rare HelmetYour ideal helmet should have at least 80 life, some resistances and “Nearby Enemies have -x% to Chaos Resistance” mod.
Body Armour
Cherrubim's MaleficenceGreat, cheap body armor which works perfectly with this build. Look for one with increased chaos damage mod as close to 80 as possible.
Gloves
Rare GlovesLook for rare gloves with high life, some resistance and chance to suppress spell damage.
Boots
Rare BootsLook for rare boots with at least 80 to maximum life, 30% increased movement speed, some resistance and chance to suppress spell damage.
Left Ring
Rare Iolite RingLook for rare Iolite ring with high life, chaos resistance and elemental resistance.
Right Ring
Rare Ring with Despair On HitLook for a rare ring with life and “Curse Enemies with Despair on Hit, with 32% increased Effect” mod. Chaos resistance or elemental resistances would be great additional mods.
Amulet
Rare AmuletWe focus on damage mods with our amulet, so look for damage over time multiplier, chaos damage over time multiplier and + 1 to Level of all Chaos/Dexterity Skill Gems mods. Life is a good additional mod to bench craft.
2 of them at the same time should be attainable quite easily after a few days in the league.
Belt
Rare Stygian ViseLook for rare Stygian Vise with high life, chaos resistance and some additional elemental resistances.
Offhand
LycosidaeLycosidae is the shield of choice for the build.
With this shield, our hits can’t be evaded and we don’t have to worry about accuracy.
Jewel
Cluster JewelsThis build uses 3 cluster jewels, 1 large and 2 medium.
On Large cluster look for 8 passives and following mods:
1) Unwaveringly evil
2) Touch of Cruelty
3) Unholy Grace
On Medium clusters look for 4 passives and following mods:
1) Circling Oblivion
2) Flow of Life
Jewel
Glorious Vanity (Xibaqua version)Endgame build also uses Glorious Vanity to convert Elemental Equilibrium keystone to Divine Flesh. This keystone helps with damage mitigation, which is also further boosted with Soul of Shakari pantheon.
Make sure your chaos resistance is capped at maximum before you allocate Divine Flesh.
Jewel
Rare JewelsOn regular rare jewels look for following mods:
1) Chaos damage over time multiplier
2) Attack speed while holding a shield
3) Increased maximum life
4) Chaos / Elemental Resistances
5) Attributes if you are lacking
Flask
Flask SetupBuild uses following flasks
1) Divine Life flask with bleed removal
2) Divine Life flask with poison immunity
3) Sulfur Flask with attack speed during flask effect
4) Quicksilver Flask
5) Jade Flask with increased armor during flask effect